Psilocybin in the Treatment of Alcoholism
The goal of this program of research is to determine whether the classic hallucinogen psilocybin is effective in the treatment of alcoholism when administered in the context of appropriate therapy and support.
In the first stage of this research, an open-label pilot study with 10 participants is being conducted to establish an appropriate dose range for use of psilocybin in alcohol dependent participants, demonstrate the feasibility of the treatment, and provide preliminary outcome and safety data.
The intervention comprises two psilocybin administration sessions and a total of 12 psychosocial treatment sessions including preparation, debriefing, and Motivational Enhancement Therapy (MET: a structured approach using the principles of Motivational Interviewing). This study is the first trial of psilocybin in the treatment of alcohol use disorder.
Recruitment for this pilot study has been completed, and the study is now in the follow-up phase. The protocol for a double-blind trial is now in development.
For more information, please contact Research Coordinator Jessica Pommy at 505-925-4190, or email Michael Bogenschutz, M.D. at firstname.lastname@example.org.