DAVID E. NICHOLS, PHD
GEORGE R. GREER, MD
MARK A. GEYER, PHD
ROLAND R. GRIFFITHS, PHD
CHARLES S. GROB, MD
DENNIS J. MCKENNA, PHD
STEPHEN ROSS, M.D.
FRANZ X. VOLLENWEIDER, MD
ROBERT J. BARNHART
ELIZABETH GORDON
WILLIAM A. LINTON
RICHARD M. WOLFE
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LYNETTE HERRING
Charles Grob
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CHARLES S. GROB, MD

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Co-Founder, Director of Clinical Research

Dr. Grob is currently Professor of Psychiatry and Pediatrics at the UCLA School of Medicine and the Director of the Division of Child and Adolescent Psychiatry at the Harbor-UCLA Medical Center. He has a long-standing interest in the history of psychiatric research with hallucinogens, and has published in the psychiatric literature and has given talks at professional meetings in this area. Dr. Grob received the first FDA approval to carry out human research with 3,4-methylenedioxymethamphetamine (MDMA). He collaborated with Drs. Dennis McKenna and Jace Callaway on a project to study the biochemical, physiological, and psychological parameters of long-term ayahuasca use in Brazil. In collaboration with Dr. Marlene Dobkin de Rios, he has examined the sociocultural context within which the use of these compounds occurs. In 2004 Dr. Grob initiated an FDA approved research investigation examining the effects of psilocybin in advanced-stage cancer patients with severe anxiety, which was completed in 2008. He is also the editor of Hallucinogens: A Reader, and the co-editor with Dr. Roger Walsh of Higher Wisdom: Eminent Elders Explore the Continuing Impact of Psychedelics.

Publications

1. Grob, C.S.: Single Case Study: Female Exhibitionism,: Journal of Nervous and Mental Disease, 173:253-256, 1985.

2. Grob, C.S.: Persistent Supersensitivity Vomiting Following Neuroleptic Withdrawal: A Case Study in an Adolescent, Biological Psychiatry, 21:398-401, 1986.

3. Grob, C.S. and Coyle, J.T.: Suspected Adverse Methylphenidate-Imipramine Interactions in Children, Journal of Developmental and Behavioral Pediatrics, 7:265-267, 1986.

4. Grob, C.S.: Substance Abuse: What Turns Casual Use into Chronic Dependence? Contemporary Pediatrics, 3:26-41, 1986.

5. Barnes, S.D., Grob, C.S. Lachman, B.S., Marsh, B.R., and Loughlin, G.M.: Psychogenic Upper Airway Obstruction Presenting as Refractory Wheezing, Journal of Pediatrics, 109:1067-1070, 1986.

6. Gallico, R.P., Burns, T.L, and Grob, C.S.: Learning Disabilities and Emotional Disorders in School-Aged Children. Boston, Little Brown & Co., 1988.

7. Bravo, G. and Grob, C.S.: Shamans, Sacraments and Psychiatrists, Journal of Psychoactive Drugs, 21: 123-128, 1989.

8. Grob, C., Bravo, G. and Walsh, R.: Second Thoughts on 3,4 -Methylenedioxymethamphetamine (MDMA) Neurotoxicity, Archives General Psychiatry, 47:288-289, 1990.

9. Grob, C.S.: Adolescence: Development and Psychopathology. In K. Davis, H. Klar, J. Coyle, (Eds.), Foundations of Psychiatry. New York, W.B. Saunders & Co., pp. 159-171, 1990.

10. Grob, C.S. and Dobkin de Rios, M.: Adolescent Drug Use in Cross Cultural Perspective, Journal of Drug Issues, 22:121- 138, 1992.

11. Liester, M.B., Grob, C.S., Bravo, G.L. and Walsh, R.N.: Phenomenology and Sequelae of 3,4- Methylenedioxymethamphetamine Use, Journal of Nervous and Mental Disease, 180:345-352, 1992.

12. Grob, C.S., Bravo, G.L., Walsh, R.N. and Liester, M.B.: The MDMA-neurotoxicity controversy: Implications for clinical research with novel psychoactive drugs, Journal of Nervous and Mental Disease, 180:355-356, 1992.

13. Grob, C.S.: Review, Healing the Split: Madness or Transcendence-A New Understanding of the Crisis and Treatment of the Mentally Ill by J.E. Nelson, Jeremy P. Tarcher, Inc, Los Angeles, 1991, in Association for Humanistic Psychology Perspective, p. 19, 1992.

14. Grob, C.S.: Depression: Pharmacological Treatment. In V. Van Hasselt and M. Hersen (Eds), Handbook of Behavioral Therapy and Pharmacotherapy for Children: A Comparative Treatment. New York, Ayllan and Bacon, pp. 171-198, 1993.

15. Dobkin de Rios, M. and Grob, C.S.: Review, Vine of the Soul: Medicine Men, their Plants and Rituals in the Colubian Amazon by R.E. Schultes and R.F. Raffaur, Synergistic Press, Boston, 1992, in Journal of Psychoactive Drugs 25:177-178, 1993.

16. Grob, C.S. and Dobkin de Rios, M.: Hallucinogens, managed states of consciousness, and adolescents: cross-cultural perspectives. In P.K. Bock (Ed), Handbook of Psychological Anthropolgy. Westport Connecticut, Greenwood Press, pp. 315-329, 1994.

17. Callaway, J.C, Airaksinen, M.M, McKenna, D.J, Brito, G.S. and Grob, C.S.: Platelet serotonin uptake sites increased in drinkers of ayahuasca, Psychopharmacology 116:385-387, 1994.

18. Grob, C.S.: Biochemical and Behavioral Effects of the Plant Hallucinogen, Ayahuasca, Neuropsychopharmacology 10:766S, 1994.

19. Grob, C.S.: Psychiatric research with hallucinogens: what have we learned? Yearbook for Ethnomedicine and the Study of Consciousness, 3:91-112, 1994.

20. Dobkin de Rios, M. and Grob, C.S.: Hallucinogens, suggestibility and adolescence in cross-cultural perspective, Yearbook for Ethnomedicine and the Study of Consciousness, 3:113-132, 1994.

21. Grob, C.S and Harman, W.W: Making sense of the psychedelic issue, Noetic Sci Rev 35:5-9,37-41, 1995.

22. Grob C.S. and Bravo G.L: Human research with hallucinogens: Past lessons and current trends, in Winkelman, M. and Andritsky, W. (Eds.), Yearbook of Cross-Cultural Medicine and Psychotherapy, Berlin: Verlag, pp. 129-142, 1995.

23. Grob, C.S, Poland, R.E, Chang, L. and Ernst, T: Psychobiologic effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans: methodological considerations and preliminary data, Behavioural Brain Research, 73:103-107, 1996.

24. Grob, C.S, McKenna, D.J, Callaway, J.C, Brito, G.S, Neves, E.S, Oberlaender, G, Saide, O.L, Labigalini, E, Tacla, C, Miranda, C.T, Strassman, R.J. and Boone, K.B: Human psychopharmacology of hoasca, a plant hallucinogen used in ritual context in Brazil, J Nervous and Mental Disease, 184:86-94, 1996.

25. Callaway, J.C, Raymon, L.P, Hearn, W.L, McKenna, D.J, Grob, C.S, Brito, G.S. and Mash, D.C: Quantitation of N,N-dimethyltryptamine and harmala alkaloids in human plasma after oral dosing with ayahuasca. J Analytical Toxicol 20:492-496, 1996.

26. Bravo, G.L. and Grob, C.S: Psychedelics and transpersonal psychiatry. In: B.W. Scotton, A.B. Chinen and J.R. Battista (Eds.), Textbook of Transpersonal Psychiatry and Psychology, New York: Basic Books, pp. 176-185, 1996.

27. Bravo, G.L. and Grob, C.S: Psychedelic psychotherapy. In: B.W. Scotton, A.B. Chinen and J.R. Battista (Eds.), Textbook of Transpersonal Psychiatry and Psychology, New York: Basic Books, pp. 335-343, 1996.

28. Grob, C.S. and Poland, R.E: MDMA: A critical reappraisal, in J.H. Lowinson, P. Ruiz, R.B. Millman and J.G. Langrod (Eds.), Substance Abuse: A Comprehensive Textbook, 3rd Edition, Baltimore: Williams and Wilkins, pp. 269-275, 1997.

29. Poland, R.E, Lutchmansingh, P, McCracken, J.T, Zhao, J.P, Brammer, G.L, Grob, C.S. and Pechnick, R.N.: Persistent dysregulation of fenfluramine induced ACTH and prolactin secretion in rats exposed to single and multiple dose MDMA, Psychopharmacology 131:411-419, 1997.

30. Grob, C.S.: La ricera umana sull'MDMA, in Schifano, F, Checchi, L, Di Furia, L, Minucci, N, Forza, G, Berto, D. and Bricolo, R. (Eds.), Ecstasy e sostanze psichedeliche, Ravenna, Italy: Regione Emilia-Romagna, Assessorato alle Politiche Sociali e Familiari, Scuola, Qualita Urbana, pp. 76-89, 1997.

31. Grob, C.S.: Psychiatric research with hallucinogens: what have we learned? Heffter Review of Psychedelic Research 1:8-20, 1998.

32. McKenna, D.J, Callaway, J.C. and Grob, C.S.: The scientific investigation of ayahuasca: a review of past and current research. Heffter Review of Psychedelic Research 1:65-77, 1998.

33. Grob, C.S.: MDMA research: preliminary investigations with human subjects. International Journal of Drug Policy 9:119- 124, 1998.

34. Grob, C.S.: Psychedelic drug research: recent developments with MDMA and ayahuasca, in R. Verres, H. Leuner and A. Dittrich (Eds.), Welten Des Bewusstseins, Berlin, Verlag fur Wissenschaft und Bildung, pp. 93-109. 1998.

35. Grob, C.S, Greer, G.R. and Mangini, M (Eds.): Therapeutic Use Of Hallucinogens, Journal of Psychoactive Drugs 30:315-428, 1998.

36. Grob, C.S, Greer, G.R. and Mangini, M: Editors' introduction: hallucinogens at the turn of the century. Journal of Psychoactive Drugs 30:315-319, 1998.

37. Callaway, J.C. and Grob, C.S: Ayahuasca preparations and serotonin uptake inhibitors: a potential combination for severe adverse interaction. Journal of Psychoactive Drugs 30:367-369, 1998.

38. Callaway, J.C, McKenna, D.J, Grob, C.S, Brito, G.S, Raymons, L.P, Poland, R.E, Andrade, E. and Mash, D.C: Pharmacokinetics of hoasca alkaloids in humans, Journal of Ethnopharmacology 65:243-256, 1999.

39. Grob, C.S: The psychology of ayahuasca, in R. Metzner (Ed.): Ayahuasca: Hallucinogens, Consciousness, and the Spirit of Nature, New York, Thunder's Mouth Press, pp. 214-249, 1999.

40. Chang, L, Ernst, T.M, Grob, C.S. and Poland R.E: Proton magnetic resonance spectroscopy in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") users. Journal of Magnetic Resonance Imaging 10:521-526, 1999.

41. Chang, L., Grob, C.S., Itti, L., Mishkin, F., Ernst, T., and Poland, R.E: Effect of ecstasy [3,4- Methylenedioxylenedioxy-methamphetamine (MDMA)] on cerebral blood flow: A co-registered SPECT and MRI study. Psychiatry Research: Neuroimaging Section 98:15-28, 2000.

42. Grob, C.S: Drug use and misuse in adolescence. The Journal of the California Alliance for the Mentally Ill 11:40-43, 2000.

43. Grob, C.S: Deconstructing ecstasy: The politics of MDMA research. Addiction Research 8:549-588, 2000.

44. Smith, L.M., Chang, L., Yonekura, M.L., Grob, C.S., Osborne, Ernst, T: Brain proton magnetic resonance spectroscopy in children exposed to methamphetamine in utero. Neurology 57:255-260, 2001.

45. Grob, C.S. Is U.S. drug policy on ecstasy scientifically justified? Journal of Addiction and Mental Health 5(2):17, 2002.

46. Grob, C.S, McKenna, D.J, Callaway, J.C, Brito, G.S, Neves, E.S, Oberlaender, G, Saide, O.L, Labigliani, E, Tacla, C, Miranda, C.T, Strassman, R.J. and Boone, K.S. Farmacologia humana da hoasca: effeitos psicologicos, in B.C. Labate and W.S. Araujo (Eds.), O Uso Ritual Da Ayahuasca, Campinas, Brazil, Mercado De Lettras, 2002.

47. Andrade, E.N, Brito, G.S, Andrade, E.S, Neves, E.S, McKenna, D.J, Cavalcante, J.W, Okimura, L, Grob, C.S. and Callaway, J.C. Farmacologica humana da hoasca: estudos clinicos, in B.C. Labate and W.S. Araujo (Eds.), O Uso Ritual Da Ayahuasca, Campinas, Brazil, Mercado De Lettras, 2002.

48. Grob, C.S. The politics of ecstasy. Journal of Psychoactive Drugs 34:143-144, 2002.

49. Cole, J, Sumnall, H. and Grob, C.S. Sorted: Ecstasy facts and fiction. The Psychologist 15:464-467, 2002.

50. Cole, J, Sumnall, H. and Grob, C.S. Where are the casualties? The Psychologist 15:474, 2002.

51. Dobkin de Rios, M, Grob, C.S. and Baker, J.R. Hallucinogens and redemption. Journal of Psychoactive Drugs 34:2390248, 2002.

52. Grob, C.S. (Ed.). Hallucinogens: A Reader, New York, Tarcher/Putnam, 2002.

53. Back-Madruga, C, Boone, K.B, Chang, L, Grob, C.S, Lee, A, Nations, H. and Poland, R.E. Neuropsychological effects of 3,4-methlyenedioxymetamphetamine (MDMA or ecstasy) in recreational users. The Clinical Neuropsychologist 17:446-459, 2003

54. Green, A.C. and Grob, C.S. Hyperactivity. In, Encyclopedia of the Neurological Sciences, Elsevier, 2003, pp. 604-608.

55. Fadiman, J, Grob, C, Bravo, G, Agar, A. and Walsh, R. Psychedelic research re-visited. Journal of Transpersonal Psychology 35:111-125, 2003.

56. Smith, H, Grob, C, Jesse, R, Bravo, G, Agar, A. and Walsh, R. Do drugs have religious import? A 40-year retrospective. Journal of Humanistic Psychology 44:120-140, 2004.

57. Grob, C.S. and Poland, R.E: MDMA: in J.H. Lowinson, P. Ruiz, R.B. Millman and J.G. Langrod (Eds.), Substance Abuse: A Comprehensive Textbook, 4th Edition, Phildadelphia: Williams and Wilkins, pp. 274-286, 2005.

58. Chang, L, Ernst, T, Speck, O. and Grob, C.S. Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities. American Journal of Psychiatry 162:361-369, 2005.

59. Chang, L, Cloak, C, Patterson, K, Grob, C.S, Miller, E.N. and Ernst, T. Enlarged striatum in abstinent methamphetamine abusers: a possible compensatory response. Biological Psychiatry 57:967-974, 2005.

60. Walsh, R. and Grob, C.S. (Eds.). Higher Wisdom: Eminent Elders Explore the Continuing Impact of Psychedelics. Albany: New York, SUNY Press (State University of New York Press), 2005.

61. Dobkin de Rios, M. and Grob, C.S. (Eds.) Ayahuasca. Journal of Psychoactive Drugs, volume 37, 2005.

62. Dobkin de Rios, M.. and Grob, C.S. Ayahuasca use in cross-cultural perspective: an introduction. Journal of Psychoactive Drugs 37:119-121, 2005

63. Doering-Silveira, E, Grob, C.S, Dobkin de Rios, M, Lopez, E, Alonso, L.B, Tacla, C, Brito, G.S, Castello, O. and Da Silveira, D.X. Ayahuasca in adolescence: a neuropsychological assessment. Journal of Psychoactive Drugs. 37:123-128, 2005.

64. Doering-Silveira, E, Grob, C.S, Dobkin de Rios, M, Lopez, E, Alonso, L.B, Tacla, C, Brito, G.S, Castello, O. and Da Silveira, D.X. Ayahuasca in adolescence: a preliminary psychiatric assessment. Journal of Psychoactive Drugs 37:129-133, 2005.

65. Dobkin de Rios, M, Grob, C.S, Lopez, E, Da Silviera, D.X, Lonso, L.K. and Doering-Silveira, E. Ayahuasca: Qualitative results. Journal of Psychoactive Drugs 37:135-139, 2005.

66. Doering-Silveira, E, Grob, C.S, Dobkin de Rios, M, Lopez, E, Alonso, L.B, Tacla, C, Brito, G.S, Castello, O. and Da Silveira, D.X. Report on psychoactive drug use among adolescents using ayahuasca within a religious context. Journal of Psychoactive Drugs 37:141-144, 2005.

67. Grob, C.S. The enigma of ecstasy: implications for youth and society. Adolescent Psychiatry 29:97-117, 2005.

68. Grob, C.S. Revisiting hallucinogen research: an experimental model with advanced-stage cancer patients and anxiety. San Francisco Medicine 79(8):22- 23, 2006.

69. Walsh, R. and Grob, C.S. Early psychedelic investigators reflect on the psychological and social implications of their research. Journal of Humanistic Psychology 46:432-448, 2006.

70. Callaway, J.C, Grob, C.S, McKenna, D.J, Nichols, D.E, Shulgin, A. and Tupper, K.W. A demand for clarity regarding a case report on the injection of 5,-methoxy-N,N-dimethyltryptamine (5-MEO-DMT) in an ayahuasca preparation 30:406-407, 2006.

71. Grob, C.S. The use of psilocybin in patients with advanced cancer and existential anxiety: in Winkelman, M., and Roberts, T. (Eds.) Psychedelic Medicine: New Evidence for Hallucinogens as Treatments. Westport, CT, Praeger/Greenwood, vol. 1, pp.205-216, 2007.

72. Walsh, R. and Grob, C.S.  Psychological health and growth:  in Winkelman, M. and Roberts, T. (Eds.) Psychedelic Medicine: New Evidence for Hallucinogens as Treatments.  Westport, CT: Praeger/Greenwood, vol. 2, pp. 213-225, 2007.

73. Grob, C.S. Substanz-unterstutzte psychotherapie am lebensende? Forschung mit
psilocybin bei krebspatienten im fortgenschrittenen stadium: in H. Jungaberle, P. Gasser, J. Weinhold and R. Verres (Eds.), Therapie mit Psychoaktiven Substanzen. Bern, Switzerland, Verlag Hans Huber, pp. 237-249, 2008.

74. Asarnow, J.R, Baraff, L.J, Berk, M, Grob, C.S, Devich-Navarro, M, Suddath, R, Piacentini, J. and Tang, L. Pediatric emergency department suicidal patients: two-site evaluation of suicide ideators, single attempters and repeat attempters. Journal of the American Academy of Child and Adolescent Psychiatry 47:958-966, 2008.

75. Grof, S, Grob, C, Bravo, G. and Walsh, R. Birthing the transpersonal. Journal of Transpersonal Psychology 40: 155-177, 2008.

76. Danforth, A.L. and Grob, C.S. Ecstasy: in G.L. Fisher and N.A. Roget (Eds.), Encyclopedia of Substance Abuse Prevention, Treatment and Recovery. London, U.K, Sage Publishers, pp. 352-354, 2009.

77. Dobkin de Rios, M. and Grob, C.S. The ritual use of psychoactive drugs: in I.P. Stolerman (Ed.), Encyclopedia of Psychopharmacology. Heidleberg, Germany, Springer Publishers, in press, 2009.

78. Grob, C.S, Danforth, A.L, Chopra, G.S, Hagerty, M.C, McKay, C.R, Halberstadt, A.L. and Greer, G.R. A pilot study of psilocybin treatment for anxiety in advanced-stage cancer patients. Submitted for publication.