This is the minimum energy conformation of (+)-3,4-methylenedioxymethamphetamine (MDMA). The molecule was minimized as the free base in vacuum, using the AM1 Hamiltonian as implemented in the Spartan (Wavefunction, Inc.) semi-empirical routines. The molecular electrostatic potential has been mapped as a mesh surface onto the electron density surface of the molecule, where more negative regions are coded as red, and more positive regions as blue. MDMA differs from hallucinogens in that it works indirectly, by the release of the neurotransmitters dopamine, serotonin, and norepinephrine from neuron terminals, while the hallucinogens such as LSD stimulate receptors directly.